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Updated: Jun 24, 2025

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
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对炎症性多神经病变和慢性炎症性脱髓化多基原蛋白神经病变的遗传分析确定了候选基因

Zhaohui Du1, Samuel Lessard1, Tejaswi Iyyanki1

  • 1Precision Medicine & Computational Biology, Sanofi, Cambridge, MA, USA.

HGG advances
|June 9, 2024
PubMed
概括

这项研究确定了慢性炎症性脱叶林性多神经病 (CIDP) 和炎症性多神经病 (IP) 的遗传风险因素. 一项全基因组关联研究在女性中发现了CIDP风险位,这表明对这些罕见的神经病变有新的遗传洞察力.

关键词:
慢性炎症性脱髓化的多神经病变.在本地化,在本地化.芬兰人 芬兰人在GWAS中,GWAS就是GWAS.门德尔的随机化在TWAS中,TWAS就是TWAS.炎症性多神经病变 (polyneuropathy) 是一种炎症性多神经病变.

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相关概念视频

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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