开发和初步验证个性化囊性纤维化药物问卷 (PCF-MQ)
Hanna Phan1, Cori L Daines2, Ti Woo3
1Department of Clinical Pharmacy, University of Michigan, College of Pharmacy, Michigan Medicine, C.S. Mott Children's Hospital, 428 Church Street, Ann Arbor, MI 48109, USA.
概括
个性化囊性纤维化药物问卷 (PCF-MQ) 显示了评估CF患者药物知识的初步有效性. 这种工具可以帮助量身定制教育,以改善囊性纤维化症的自我管理.
科学领域:
- 医学教育 医学教育
- 患者自我管理
- 呼吸系统医学 呼吸系统医学
背景情况:
- 评估药物知识对于囊性纤维化 (CF) 的有效自我管理至关重要.
- 现有的工具可能无法充分捕捉特定于个人的治疗方案的个性化药物知识.
- 开发定制的评估工具可以确定CF (pwCF) 患者的教育需求.
研究的目的:
- 描述个性化CF药物问卷 (PCF-MQ) 的开发和评分.
- 评估PCF-MQ在测量对处方CF药物的知识方面的初步有效性.
- 评估PCF-MQ在确定pwCF的教育机会方面的实用性.
主要方法:
- 该PCF-MQ被给予了12岁以上的参与者,他们服用CF药物.
- 研究人员检查了PCF-MQ分数,疾病管理知识 (KDM-CF) 和囊性纤维化药物信仰问卷 (CF-MBQ) 之间的相关性.
- 统计分析使用了斯皮尔曼rho相关性,从医疗记录中抽取了处方方案.
主要成果:
- 招募了60名患有CF的人;分析了57人的数据.
- 平均PCF-MQ总得分为77.8%,知识因药物不同而有所不同 (例如,levalbuterol的58.3%,ivacaftor的100%).
- PCF-MQ总分数与KDM-CF分数有显著的相关性 (斯皮尔曼Rho=0.32-0.59,p <0.05),但与CF-MBQ分量级 (p >0.05) 没有相关性.
结论:
- PCF-MQ证明了初步有效性,与一般CF知识相关,但与健康信念无关.
- PCF-MQ为评估CF患者的特定药物知识提供了实际优势.
- 需要对更大的样本大小进行进一步验证,以确认PCF-MQ在个性化CF护理中的实用性.
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