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Updated: Jun 24, 2025

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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类似于乌比奎丁的修饰依赖于蛋白质体降解和疾病治疗

Tiantian Wang1, Jie Jiang1, Xue Zhang1

  • 1Center for Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Trends in molecular medicine
|June 9, 2024
PubMed
概括

乌比奎类 (UBL) 修改,而不仅仅是乌比奎,驱动蛋白质酶体降解. 本综述探讨了独特的UBL-蛋白酶体系统 (UBLPS) 及其在疾病中的作用,并提出了治疗策略.

关键词:
消耗肌肉的疾病 消耗肌肉的疾病神经退行性疾病的神经退行性疾病蛋白质群体的降解蛋白酶体调节剂 蛋白质酶体调节剂这是一种类似于乌比奎的修饰.类似于ubiquitin的蛋白酶体系统

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