处女的重复性巨乳巨 (乳房缩). 一个案例报告
V Cheshuk1, M Anikusko2, V Kozina2
1Bogomolets National Medical University, Kyiv, Ukraine.
Experimental oncology
|June 9, 2024
概括
处女性巨头 (VGM) 治疗具有挑战性. 这一案例突显了使用乳房保护手术和激素治疗成功管理复发性VGM,从而减轻了身体和心理的痛苦.
科学领域:
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
- 病理学 病理学 病理学
背景情况:
- 处女性巨乳 (VGM) 是一种罕见的良性乳腺疾病,病因不明确,治疗选择具有挑战性.
- 目前的治疗方法,如保守的方法是无效的,而乳房切除术是过度创伤,需要替代方法.
研究的目的:
- 为了呈现一种复发性处女性巨头 (VGM) 的病例.
- 评估乳腺保护手术与辅助激素治疗相结合的疗效,用于治疗复发性VGM.
- 讨论在复发性VGM.中发生的基因病理学发现和受体表达.
主要方法:
- 2014年,一名患有处女性巨乳 (VGM) 的患者接受了减少性乳房整形手术.
- 9年后发生了复发,导致了第二次手术,包括切除和减少乳房整形.
- 组织病理学分析显示了广泛的纤维化,瘤和纤维腺瘤,具有高雌激素和孕激素受体表达 (70%).
- 开始使用他莫西芬 (10毫克/天) 的激素治疗,随后进行动态监测.
主要成果:
- 在最初的手术9年后,该患者经历了VGM的复发.
- 组织病理学证实了广泛的纤维化,hamartomas和纤维腺瘤与高激素受体表达.
- 在第二次手术干预后,服用他莫西芬的辅助激素治疗被处方.
结论:
- 乳腺保护手术可以成为治疗复发性处女性巨头 (VGM) 的可行选择.
- 辅助激素治疗,如他莫西芬,可能对患有高雌激素和孕激素受体表达的患者有益.
- 有效管理VGM可以减轻显著的心理,社会和身体痛苦.
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