铁酸对胚胎发育的保护作用通过改善肉的抗氧化功能来改善胚胎的热操纵
Shixiong Lai1, Panqi Wei1, Ailin Wang1
1College of Animal and Veterinary Sciences, Southwest Minzu University; Key Laboratory of Animal Medicine at Southwest Minzu University of Sichuan Province, Chengdu, 610041, PR China.
Journal of thermal biology
|June 9, 2024
概括
浸泡肉胚胎的酸 (FA) 减轻了热操纵 (TM) 对发育的负面影响. FA增强了肝脏的抗氧化能力,提高了的存活率,提供了实际的家禽行业应用.
科学领域:
- 禽畜科学 禽畜科学 禽畜科学
- 胚胎学 胚胎学
- 动物营养 动物营养
背景情况:
- 肉化期间的热操纵 (TM) 可能会对胚胎发育和小质量产生负面影响.
- 酸 (FA) 是一种天然抗氧化剂,有可能减轻家禽生产中的压力因素.
研究的目的:
- 研究酸 (FA) 溶液浸泡在肉胚胎中的有效性,以抵消热操纵 (TM) 的不良影响.
- 建立一个理论和实验基础,在家禽养殖中整合TM和FA.
主要方法:
- 120个肉蛋被分为对照,TM和TM + FA组.
- 从第7天到第16天,每天18小时暴露在39.5°C/65%的湿度下.
- 从第6-8天开始,TM + FA组每天接受FA溶液浸泡 (80 mg/L6分钟)
主要成果:
- TM显著增加了死亡胚胎和弱小的小;FA治疗降低了这些率.
- FA 改善了血清超氧化解突变酶 (SOD) 活性和肝脏SOD和酶 (CAT) 活性.
- 在肝脏中,FA治疗上调了Nrf2和SOD基因表达,增强了抗氧化能力.
结论:
- 酸有效地减轻肉胚胎的热操纵引起的压力.
- 通过Nrf2-Keap1通路,FA增强了肝脏的抗氧化防御机制.
- 在TM条件下,FA应用程序提供了一种可行的策略,以改善肉胚胎发育和的质量.
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