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Updated: Jun 24, 2025

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在乳腺癌中,SMARCC2沉默通过调节染色质可访问性来抑制瘤原性激活

Zhaoran Sun1, Zhongkun Wang2, Yirao Zhang1

  • 1Jiangsu Key Laboratory of Brain Disease and Bioinformation, Xuzhou Medical University, Xuzhou, China.

Biochemical and biophysical research communications
|June 9, 2024
PubMed
概括

作为SWI/SNF复合体的一个组成部分,SMARCC2令人惊地促进了乳腺癌的生长和干细胞特征. 它的耗尽通过降低Ras-PI3K通路的调节来抑制瘤,从而将SMARCC2确定为潜在的治疗标.

关键词:
癌症干细胞是癌症的干细胞.染色体的可访问性 染色体的可访问性在PI3K中,PI3K是指PI3K.在SMARCC2中,我们可以使用SMARCC2.在 SWI/SNF 中.

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