基于聚乙烯酸盐-共甲酸盐的食品接触用品中的挥发性有机化合物的特征,危害识别和风险评估
Hanke Li1, Hongjian Miao2, Lichang Chen3
1National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China.
概括
这项研究确定了237种挥发性有机化合物 (VOC) 在聚 (丁烯基酸盐-联合甲酸盐) (PBAT) 食品接触物品中. 虽然整体风险是可以接受的,但特定的VOC如牛索兰需要优先关注PBAT化学安全.
科学领域:
- 食品接触材料安全与食品接触材料安全
- 聚合物化学 聚合物化学
- 毒理学 毒理学 毒理学
背景情况:
- 越来越多的毒理问题涉及基于聚乙烯基酸盐-共甲酸盐 (PBAT) 的食品接触用品 (FCAs).
- 从PBAT FCAs迁移的物质的化学表征和风险评估不足.
- 需要了解已识别的物质的分布模式和潜在的基因毒性/致癌性危害.
研究的目的:
- 在基于PBAT的FCAs和颗粒中描述挥发性有机化合物 (VOCs).
- 评估与已识别的VOCs相关的化学危险和风险.
- 为了提高PBAT FCAs的化学安全性,优先考虑引起关注的物质.
主要方法:
- 在50批基于PBAT的FCAs和10批PLA/PBAT颗粒中的VOC的表征.
- 在10个化学品类别中使用分子描述符识别237种挥发性有机化合物.
- 危险分类整合公共数据和风险/危险系数 (HQ) 计算.
主要成果:
- 237个具有特征分布模式的VOC被确定.
- 34 鉴定出具有基因毒性或致癌危害的挥发性有机化合物,具有更高的平均分子量.
- 所有的VOC都具有可接受的风险 (风险<10−4或HQ<1),但特定的化合物显示出不可忽视的基因毒性/致癌风险 (风险>10−6).
结论:
- 基于PBAT的FCA含有复杂的VOC混合物,具有不同的危险概况.
- 由于存在潜在的基因毒性/致癌风险,牛兰,布罗拉克,N,N-二甲基胺,2-布托西乙醇,醇和1,2,3-三烯应优先考虑.
- 需要进一步的研究和监管关注,以确保基于PBAT的FCA的化学安全.
更多相关视频
05:05Quantification of Polybutylene Adipate Terephthalate-based Micro- and Nano-plastics from Soil Using Proton Nuclear Magnetic Resonance Spectroscopy
Published on: June 6, 2025
55
10:12Extraction of Organochlorine Pesticides from Plastic Pellets and Plastic Type Analysis
Published on: July 1, 2017
11.6K
相关概念视频
01:20Types of Step-Growth Polymers: Polyesters
2.2K
The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the...
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the...
2.2K
01:26Polymer Classification: Stereospecificity
2.4K
Polymerization generates chiral centers along the entire backbone of a polymer chain. Accordingly, the stereochemistry of the substituent group has a significant effect on polymer properties. Polymers formed from monosubstituted alkene monomers feature chiral carbons at every alternate position in the polymer backbone. Relative to the predominant orientation of substituents at the adjacent chiral carbons, the polymer can exist in three different configurations: isotactic, syndiotactic, and...
2.4K
01:00Characteristics and Nomenclature of Homopolymers
3.0K
Polymers that are made up of identical monomer units are called homopolymers. Only one repeating unit is involved in the construction of the homopolymer structure. For example, as depicted in Figure 1, polypropylene is a homopolymer constituted of propylene monomers. Here, the only repeating unit in the polymer chain is propylene.
3.0K
01:14Polymer Classification: Architecture
2.7K
Polymers are classified as linear or branched on the basis of their chain architecture. The polymer chains in linear polymers have a long chain-like structure with minimal to no branching at all. Even if a polymer features large substituent groups on the monomer, which appear as branches to the skeleton, it is not considered a branched polymer. A branched polymer contains secondary polymer chains that arise from the main polymer chain. The branching occurs when the polymer growth shifts from...
2.7K
01:21Polymer Classification: Crystallinity
2.8K
Unlike ionic or small covalent molecules, polymers do not form crystalline solids due to the diffusion limitations of their long-chain structures. However, polymers contain microscopic crystalline domains separated by amorphous domains.
Crystalline domains are the regions where polymer chains are aligned in an orderly manner and held together in proximity by intermolecular forces. For example, chains in the crystalline domains of polyethylene and nylon are bound together by van der Waals...
Crystalline domains are the regions where polymer chains are aligned in an orderly manner and held together in proximity by intermolecular forces. For example, chains in the crystalline domains of polyethylene and nylon are bound together by van der Waals...
2.8K
02:35Free-Radical Chain Reaction and Polymerization of Alkenes
7.8K
The conversion of alkenes to macromolecules called polymers is a reaction of high commercial importance. The structure of the polymer is defined by a repeating unit, while the terminal groups are considered insignificant. The average degree of polymerization represents the number of repeating units in the polymer molecule and is denoted by the subscript n.
7.8K