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辅助生殖技术是否与胎儿窒息有关? 一个回顾意大利案例-控制研究

Elena Osella¹, Carmen Imma Aquino¹, Sofia Colagiorgio¹

¹Department of Gynaecology and Obstetrics, Ospedale Maggiore della Carità, Novara, Italy; Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC

|June 9, 2024

概括

辅助生殖技术 (ART) 可能会显著增加胎儿窒息的风险. 这项研究发现ART怀孕的风险增加了七倍,突出显示需要进一步调查原因.

科学领域:

产科和妇科产科和妇科
生殖医学生殖医学
新生儿健康新生儿健康

背景情况:

胎儿窒息是一种严重的疾病,具有多种已知的危险因素.
辅助生殖技术 (ART) 对胎儿窒息风险的潜在贡献尚未得到充分证实.

研究的目的:

调查辅助生殖技术 (ART) 是否与胎儿窒息风险增加有关.
用于量化通过ART怀孕的胎儿窒息的风险.

主要方法:

追溯性,分析性,病例控制研究设计.
162例胎儿窒息病例与361例没有胎儿窒息病例的对照病例进行比较.
包括32个通过ART怀孕的怀孕,以及有关卵子捐赠的详细信息.

主要成果:

与对照组相比,在ART怀孕中观察到胎儿窒息的发生率显著更高 (75%).
在ART怀孕中,胎儿窒息的风险大约增加了7倍.
这一发现与现有的,尽管有限的科学文献相一致.

结论:

辅助生殖技术 (ART) 似乎是胎儿窒息的重要危险因素.
关联ART与胎儿窒息的潜在机制 (发病机制) 需要紧急和彻底的调查.
进一步的研究至关重要,以了解和潜在地减轻这种在ART怀孕怀孕的高风险.

关键词:

辅助生殖技术是一种辅助生殖技术.脑性麻脑性麻是一种产妇内窒息症产妇内窒息症新生儿重症监护室新生儿重症监护室产科的结果.

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