在急性前膜炎中复发的风险
James T Brodie1, Aliyah Z Thotathil2, Charlotte A Jordan1
1Department of Ophthalmology, Greenlane Clinical Centre, Te Whatu Ora Health New Zealand, Auckland, New Zealand; Department of Ophthalmology, University of Auckland, Auckland, New Zealand.
Ophthalmology
|June 9, 2024
概括
大约一半的急性前膜炎 (AAU) 患者在同一个眼睛中出现复发,四分之一的人在另一只眼睛中出现复发. 病毒性脑膜炎呈现出最高的风险为ipsilateral复发.
科学领域:
- 眼科医生 眼科 眼科
- 免疫学 免疫学 免疫学
背景情况:
- 急性前膜炎 (AAU) 是一种常见的眼内炎症形式.
- 了解复发模式和风险因素对于管理AAU和预防视力丧失至关重要.
研究的目的:
- 为了确定急性前膜炎 (AAU) 患者的复发频率.
- 在ipsilateral和contralateral眼中识别与AAU复发相关的风险因素.
主要方法:
- 在一个单一的三级眼科中心进行了一项回顾性队列研究.
- 分析了2008年至2021年间2092名患有AAU的患者的数据.
- 使用卡普兰-梅尔估计器和考克斯回归模型来评估复发率和风险因素.
主要成果:
- 复发发生在45.5%的ipsilateral眼睛和27.3%的 contralateral眼睛.
- 年龄较大,毛利人和亚洲族裔,人类白细胞抗原B27 (HLA-B27) /炎症性关节炎和病毒性脑膜炎与增加的两侧复发风险有关.
- 毛利族和帕西菲卡族,以及HLA-B27/炎症性关节炎是 contralateral眼睛参与的危险因素.
结论:
- AAU经常复发,影响近一半的患者在ipsilateral眼睛和四分之一的患者在对立眼睛.
- 病毒性脑膜炎与最高的ipsilateral复发风险和最低的 contralateral风险有关.
- 识别患有AAU复发风险因素的患者对于适当的管理和咨询来预防视力损伤至关重要.
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