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Updated: Jun 24, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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IGF-II调节 lysyl氧化酶 propeptide,并通过基本螺旋环-螺旋环 E40 中介其作用,部分通过基本螺旋环-螺旋环 E40 中介

Adegboyega Timothy Adewale1, Shailza Sharma1, Joe E Mouawad1

  • 1Department of Medicine, Medical University of South Carolina, Charleston 29425, 96 Jonathan Lucas Street, MSC637, SC, USA.

Matrix biology : journal of the International Society for Matrix Biology
|June 9, 2024
PubMed
概括

胰岛素类生长因子II (IGF-II) 通过调节LOX-Propeptide (LOX-PP) 和BHLHE40转录因子来驱动系统性硬化相关的肺纤维化 (SSc-PF). 向IGF-II,BHLHE40和LOX-PP可能会阻止SSc-PF的进展.

关键词:
骨形态遗传蛋白 1 骨形态遗传蛋白 1类E 基本螺旋环螺旋蛋白 40类似胰岛素的增长因子IILysyl 氧化酶 Propeptide 莱西尔氧化酶 Propeptide 莱西尔氧化酶 propeptide 莱西尔氧化酶 propeptide 莱西尔氧化酶系统性硬化 肺纤维化 肺纤维化一个类似托洛伊德的11

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