一个新的编码系统用于识别左心室旋转模式及其与心肌功能相关性的新编码系统
Vicente Mora1, Juan Geraldo1, Ildefonso Roldán2
1Department of Cardiology, Hospital Universitario Dr Peset, 46017, Valencia, Spain.
Annals of biomedical engineering
|June 9, 2024
概括
一个新的编码系统可以识别左心室的旋转模式,区分扭转和刚性旋转. 这种方法与心肌功能和左心室喷射率 (LVEF) 相对应,改善了临床评估.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 生物机械工程 生物机械工程
背景情况:
- 左心室喷射分数 (LVEF) 对于评估心脏功能至关重要.
- 目前的临床编码系统在区分左心室 (LV) 旋转模式方面缺乏特异性.
- 了解LV旋转力学是评估心肌功能的关键.
研究的目的:
- 引入和验证一个替代的编码系统来识别不同的LV旋转模式.
- 为了将这些已识别的旋转模式与心肌功能相关联,特别是跨壁全球纵向菌株 (tGLS) 和LVEF.
- 评估拟议系统在健康受试者和患有LV缩 (LVH) 的患者中的临床适用性.
主要方法:
- 利用心声回声成像和斑点跟踪来得出tGLS和旋转参数.
- 定义了一个旋转梯度来量化扭转 (正值) 和刚性旋转 (负值).
- 评估了87名健康受试者和248名LVH患者,根据旋转模式和心肌功能对其进行分类.
主要成果:
- 拟议的系统成功地区分了扭转和刚性旋转模式.
- 扭曲在健康对照组和正常心肌功能 (tGLS ≥17%) 的LVH患者中普遍存在.
- 在患有心肌功能障碍的LVH患者中 (tGLS<17%),扭曲发生在83.3%的患者中,刚性旋转发生在16.7%的患者中;所有刚性旋转病例都有LVEF<50%.
- 旋转梯度值与LVEF有很强的相关性 (r = 0.73,p < 0.001).
结论:
- 新的编码系统有效地识别了特定的LV旋转模式.
- 该系统为将旋转力学与心肌功能和LVEF联系起来提供了有价值的工具.
- 它为改善心血管评估中的诊断和预后能力提供了潜力.
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