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对接受放射治疗的癌症老年患者进行管理的老年评估:一个集群随机对照试点研究
Marit Slaaen1,2, Inga Marie Røyset3,4,5, Ingvild Saltvedt6,7
1The Research Centre for Age-Related Functional Decline and Disease, Innlandet Hospital Trust, Box 68, 2312, Ottestad, Norway.
BMC medicine
|June 9, 2024
概括
老年评估和管理 (GAM) 在接受放射治疗 (RT) 的老年癌症患者中没有改善功能或生活质量 (QoL). 未来的研究应该集中在脆弱的患者身上,以澄清GAM.
科学领域:
- 老年瘤学 老年瘤学
- 放射治疗研究的研究.
- 医疗服务研究 医疗服务研究
背景情况:
- 老年评估和管理 (GAM) 改善了接受手术或化疗的老年癌症患者的治疗结果.
- 在放射治疗 (RT) 环境中,GAM的有效性和成本效益仍然不清楚.
- 本研究研究了GAM对RT患者的功能和生活质量 (QoL) 的影响.
研究的目的:
- 评估老年评估和管理 (GAM) 干预对接受放射治疗 (RT) 的老年患者身体功能和生活质量 (QoL) 的影响.
- 在这个患者群体中评估GAM干预的成本效益.
- 探索综合专家和初级卫生服务在老年RT患者管理中的作用.
主要方法:
- 一项挪威集群随机对照试点研究,涉及32个市政/城市地区,随机分为干预或传统护理.
- 这项干预包括在RT开始时在医院内启动GAM,并根据个人适应的计划和在RT后8周的市政护士领导的随访.
- 参与了178名年龄≥65岁的转诊RT的患者,以身体功能 (EORTC QLQ-C30) 为主要结局.
主要成果:
- 在GAM干预组和对照组之间,在预定义的结局,包括身体功能和QOL方面,没有发现显著差异.
- 干预组接受了更多的疗效RT和更高的辐射剂量.
- 老年医疗评估和管理 (GAM) 费用占干预组总医疗服务费用的3%.
结论:
- 老年评估和管理 (GAM) 干预措施对以患者为中心的结果或医疗服务成本在老年RT患者的异质队列中没有影响,主要是健康的个体.
- 未来的研究应该针对更同质的前脆弱和脆弱患者群体,以确定GAM在RT环境中的作用和最佳组织.
- 澄清那些在RT中从GAM中受益最多的特定患者子组对于优化护理提供至关重要.
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