生物酸盐增强漂白凝在质上具有早期侵蚀病变的有效性和安全性
Rafael Dascanio1, Rafael Antonio de Oliveira Ribeiro2, Camila Siqueira Silva Coelho1
1Department of Restorative Dentistry, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.
概括
将生物酸盐 (BioS) 添加到35%过氧化 (HP) 凝中,保持了牙美白的有效性,同时降低了细胞毒性和氧化应激,特别是在早期侵蚀的牙中.
科学领域:
- 牙科材料科学 牙科材料科学
- 生物材料工程 生物材料工程
- 生物化学 生化学
背景情况:
- 牙美白程序通常使用过氧化 (HP) 凝.
- 早期的牙磨损可以增加脉炎症和漂白期间过敏的风险.
- 生物酸盐 (BioS) 是一种具有潜在治疗性能的生物材料.
研究的目的:
- 为了评估35%HP凝与10%生物酸盐 (BioS) 的有效性和细胞毒性,对声音和早期侵蚀的面膜进行评估.
- 评估BioS结合对HP扩散,氧化应激和细胞活力的影响.
主要方法:
- 乳/牙盘经过侵蚀周期,并用35%的HP处理,HP用BioS (HP_BioS),BioS或对照.
- 漂白是在三次30分钟的会议中进行的.
- 测量了颜色变化,HP扩散,细胞活力 (MTT测定) 和氧化应激.
主要成果:
- HP_BioS的漂白效果与单独使用HP的漂白效果相当.
- 纳入BioS显著降低了HP扩散,并减轻了受侵蚀的质中的氧化应激.
- 与HP相比,HP_BioS表现出明显更高的细胞活力,特别是在侵蚀性条件下.
结论:
- 将BioS纳入35%HP凝中,可以保持漂白效果,同时减少细胞毒性和氧化应激.
- 该BioS配方显示承诺更安全的牙漂白在早期牙磨损的患者.
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