预测患有尿管盆结阻塞的儿童的临床显著事件
Clara Wolmer1, Jean Delmas2, Silvia Pecorelli1
1Department of Pediatric Surgery, Hopital Pellegrin-Enfants, CHU Bordeaux, France.
Frontiers in pediatrics
|June 10, 2024
概括
在患有尿道接阻塞 (UPJO) 的儿童中,在产前超声波中,骨的前后直径 (APD) 在预测显著的临床事件方面比尿路扩张 (UTD) 更有效.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 医疗成像医学成像
- 新生儿手术 新生儿手术
背景情况:
- 泌尿外皮交点阻塞 (UPJO) 是新生儿水的常见原因之一.
- 目前UPJO的管理策略各不相同,缺乏普遍的标准化.
- 新的尿道扩张 (UTD) 分类旨在标准化超声波描述,并预测儿科水解的结果.
研究的目的:
- 为了比较UTD分类的预测能力与骨的前后直径 (APD).
- 评估UPJO儿童在生命第一年内临床显著事件的预测.
主要方法:
- 对患有UPJO的儿童进行前性单心队列研究.
- 儿科放射科医生,对结果盲目,使用UTD分类超声波和测量APD.
- 临床上显著的事件被定义为增加的骨盆扩张,发烧性尿路感染 (fUTI) 或功能受损.
主要成果:
- 该研究包括28名儿童,其中20人经历了临床显著事件.
- 产前APD (APD-A) 是预测显著临床事件的最有效的个体标准 (AUC = 0.867).
- 产前APD>15毫米是预测扩张增加>5毫米的最重要的标志物.
结论:
- 产前APD测量是UPJO中不良结果的高度有效预测器.
- 对于UPJO中重大事件的UTD分类的预测价值需要进一步调查.
- 在产前超声波上测量APD是一种宝贵的工具,用于新生儿水缩的风险分层.
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