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Updated: Jun 24, 2025

Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions
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Published on: August 2, 2018

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分支链α-酸有氧激活血管细胞中的HIF1α信号传递

Wusheng Xiao1,2,3,4, Nishith Shrimali1, William M Oldham1

  • 1Divisions of Cardiovascular Medicine and Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

bioRxiv : the preprint server for biology
|June 10, 2024
PubMed
概括

分支链α-酸 (BCKA) 在正常氧气条件下激活催氧诱导因子1α (HIF1α) 信号. 这种BCKA-HIF1α通路影响血管光滑肌肉细胞功能,可能与肺动脉高血压有关.

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