相关实验视频

Updated: Jun 24, 2025

Using Optogenetics to Reverse Neuroplasticity and Inhibit Cocaine Seeking in Rats
09:43

Using Optogenetics to Reverse Neuroplasticity and Inhibit Cocaine Seeking in Rats

Published on: October 5, 2021

2.5K

白球中的分子和电路决定因素调解了可卡因诱导的行为可塑性的控制

Guilian Tian, Katrina Bartas, May Hui

    bioRxiv : the preprint server for biology
    |June 10, 2024
    PubMed
    概括

    环球外 (GPe) 帕瓦尔胺阳性细胞通过调节多巴胺通路来获得可卡因奖励. 来自迷香的酸,通过降低GPe兴奋度,显示出治疗精神刺激剂使用障碍的潜力.

    更多相关视频

    Rodent Brain Microinjection to Study Molecular Substrates of Motivated Behavior10:05

    Rodent Brain Microinjection to Study Molecular Substrates of Motivated Behavior

    Published on: September 16, 2015

    14.4K
    Stereotaxic Microinjection of Viral Vectors Expressing Cre Recombinase to Study the Role of Target Genes in Cocaine Conditioned Place Preference08:22

    Stereotaxic Microinjection of Viral Vectors Expressing Cre Recombinase to Study the Role of Target Genes in Cocaine Conditioned Place Preference

    Published on: July 30, 2013

    18.6K

    相关概念视频

    Drug Abuse and Addiction: Pharmacological Phenomena01:15

    Drug Abuse and Addiction: Pharmacological Phenomena

    Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
    465
    CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

    CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

    CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
    183