人工智能启用预测单导电心电图的心力衰竭风险
Lovedeep S Dhingra1, Arya Aminorroaya1, Aline F Pedroso1
1Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
medRxiv : the preprint server for health sciences
|June 10, 2024
概括
使用单导电心电图 (ECG) 的人工智能 (AI) 算法有效预测心力衰竭 (HF) 风险. 这种AI-ECG方法为基于社区的高频风险评估提供了一个可扩展的策略.
科学领域:
- 心脏病学 心脏病学
- 人工智能的人工智能
- 医疗器械 医疗器械
背景情况:
- 尽管有可用的治疗方法,可扩展心力衰竭 (HF) 风险分层仍然是一个挑战.
- 便携式单导电心电图 (ECG) 设备为大规模风险评估提供了潜力.
研究的目的:
- 评估一种人工智能 (AI) 算法,用于使用杂的单导电心电图来预测高频风险.
- 评估AI-ECG在识别有左心室缩功能障碍 (LVSD) 风险的个体方面的表现.
主要方法:
- 一项多队列研究使用了回顾性 (耶鲁纽黑文卫生系统) 和前性 (英国生物银行,ELSA-巴西) 数据.
- 一个适应噪声的AI-ECG模型被应用到I ECG以识别LVSD和预测新发性HF.
- 使用歧视指标,AI-ECG的表现与已确定的风险得分 (PCP-HF,PREVENT) 进行了比较.
主要成果:
- 人工智能电脑电图 (AI-ECG) 确定了3至7倍增加HF风险的个体,更高的模型概率与增加的危险相关.
- 在AI-ECG中,跨队列的新发性HF受到强烈的歧视 (C统计 0.725-0.833).
- 与PCP-HF和PREVENT方程相比,纳入AI-ECG可以改善风险预测,显示C统计,IDI和NRI的显著改善.
结论:
- 使用I心电图的适应噪声的人工智能模型可以有效地分层心力衰竭风险.
- 这种AI-ECG方法表明,基于便携式和可穿戴设备的高频风险分层是一个有希望的策略.
- 这些发现支持使用可访问的ECG技术进行广泛的基于社区的高频风险评估的潜力.
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