深度神经网络通过12导电心电图检测区域壁壁运动异常和临床前心血管疾病
Tanner Carbonati1, Parastou Eslami2, Jonathan W Waks3
1Philips Healthcare, Paris, France.
medRxiv : the preprint server for health sciences
|June 10, 2024
概括
深度神经网络可以从12导电心电图 (ECG) 中识别区域壁运动异常和左心室功能减弱. 这种工具可能有助于对患者进行进一步的心脏成像和风险分层.
科学领域:
- 心脏病学 心脏病学
- 人工智能的人工智能
- 医疗成像医学成像
背景情况:
- 识别区域壁运动异常 (RWMA) 对心血管疾病诊断和风险分层至关重要.
- 缺血性心脏病的管理严重依赖于检测RWMAs.
研究的目的:
- 开发和验证一个深度神经网络 (DNN),能够仅使用标准的12导电心电图 (ECG) 数据检测RWMA.
- 评估DNN识别不同程度的左心室功能障碍和右心室低运动的能力.
主要方法:
- 一个卷积神经网络被训练在ECG数据从患者与并发心声图.
- 该模型确定了RWMA,RV低运动和左心室喷射率 (LVEF) 值 (≤50%,≤40%,≤35%).
- 使用接收器操作特征曲线 (AUC) 下的面积来评估性能,并通过Cox模型评估未来的急性冠状动脉事件风险.
主要成果:
- 在确定RWMA (AUC 0.87) 和LVEF ≤40% (AUC 0.93) 时,DNN实现了高准确度.
- 该模型在检测RV低运动 (AUC 0.888) 和LVEF ≤35% (AUC 0.876) 中表现出强的性能.
- 根据模型确定RWMA的患者面临2.8倍的未来急性冠状动脉事件的风险增加.
结论:
- 一个DNN可以有效地识别RWMA和左心室功能减少从12导电心电图.
- 这种人工智能工具显示出作为心脏成像选的非侵入性查方法的潜力.
- 使用心电图数据与DNN可以改善心血管疾病的早期检测和管理.
相关概念视频
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