对急性上部胃肠道出血的内镜:随机对照试验的系统审查和网络元分析的协议
Xiaofang Tang1,2, Lixi Long1,2, Xiaoyun Wang1,2
1Emergency Department of West China Hospital/Emergency and Trauma Nursing Department of West China Nursing School.
International journal of surgery protocols
|June 10, 2024
概括
这项研究系统地审查了急性上部胃肠道出血 (AUGIB) 的内镜时间. 它旨在澄清内镜干预的最有效时间,以改善AUGIB管理中的患者结果.
科学领域:
- 胃肠病学 胃肠病学
- 内镜干预措施的内镜干预
- 临床试验方法论 临床试验方法论
背景情况:
- 关于内镜治疗急性上部胃肠道出血 (AUGIB) 的最佳时间存在相互矛盾的证据.
- 需要进行系统审查和元分析,以综合AUGIB内镜定时的现有数据.
研究的目的:
- 系统地审查并对AUGIB各种内镜计时策略的疗效进行元分析.
- 提供全面的证据来指导AUGIB管理中的临床决策.
主要方法:
- 在多个数据库 (PubMed,Embase等) 中进行系统搜索. 将进行至2023年7月.
- 将包括评估AUGIB不同内镜时间的随机对照试验.
- 将使用贝叶斯网络元分析来比较初级和二级结果,包括静血,死亡率,再出血和住院时间.
主要成果:
- 该研究将综合选定随机对照试验的数据.
- 网络元分析将提供不同的内镜计时方法的比较有效性.
- 结果将在同行评审期刊上发表.
结论:
- 这个网络的元分析将为AUGIB提供关于内镜干预的最佳时间的强有力的证据.
- 预计这些发现将为管理急性上部胃肠道出血的临床实践指南提供信息.
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