在中研究,蛋白激酶抑制和分子对接研究,对本齐米达衍生物的研究

Kamaraj Karthick1, Kamaraj Abishek2, Ebenezer Angel Jemima3

  • 1Department of Chemistry, Rajalakshmi Institute of Technology, Chennai, Tamil Nadu, India.

概括

西米达衍生物通过抑制CDK4/CycD1和Aurora B.等关键激酶蛋白来显示出作为抗癌药物的前景. 在 silico 研究证实了它们对潜在的临床开发有利的药理动力学特性.

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