视盘出血和视神经变化的特征在急性初级角度关闭后
Hengli Zhang1, Yawen Li1, Yizhen Tang2
1Department of Ophthalmology, Shijiazhuang People's Hospital, Shijiazhuang, China.
Frontiers in neurology
|June 10, 2024
概括
在急性初级角关闭 (APAC) 发作期间,光盘出血很常见,并且与高眼内压 (IOP) 持续时间有关. 有效的IOP管理对于在APAC事件后的视觉恢复至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 视网膜成像 视网膜成像
背景情况:
- 急性初级角闭合 (APAC) 是不可逆转失明的主要原因,特别是在中国.
- 在亚太地区发作期间的光盘出血 (ODH) 尚未得到充分研究,对其特征和对视神经健康的影响的数据有限.
- 了解亚太地区的ODH对于管理这种眼科紧急情况至关重要.
研究的目的:
- 为了分析光盘出血 (ODH) 的特征,患者经历了他们的第一个急性初级角关闭 (APAC) 情节.
- 调查视神经的变化,包括视网膜神经纤维层厚度 (RNFLT) 和平均偏差 (MD),与ODH和眼内压力 (IOP) 相关的控制.
- 为了将ODH特征与亚太地区患者中升高IOP的持续时间和严重程度相关联.
主要方法:
- 对32名患有APAC的32名患者的32只眼睛进行了回顾性分析.
- 评估最高眼内压力 (IOP),其持续时间,光盘出血 (ODH),视网膜神经纤维层厚度 (RNFLT) 和平均偏差 (MD).
- 在受影响的眼睛 (ODH组) 和不受影响的对侧眼睛 (对照组) 之间进行比较.
主要成果:
- 在亚太地区,ODH很常见,火焰和碎片形状占主导地位.
- 在ODH的程度和最高IOP的持续时间 (p < 0.001) 之间发现了正相关性.
- RNFLT显示过渡性加厚,随后是稀薄,稳定6个月,而MD部分改善,受ODH范围和IOP持续时间的影响.
结论:
- 在APAC期间的光盘出血与长时间的高眼内压有关.
- ODH的范围和升高IOP的持续时间显著影响视野损伤 (MD).
- 迅速有效的IOP管理对于APAC攻击后视觉功能恢复至关重要.
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