多器官系统在COVID-19中的参与与更糟糕的预后有关
Eric Lam1, Sandra Gomez-Paz2, Luis Fernando Gonzalez-Mosquera1
1Nassau University Medical Center Department of Medicine East Meadow, NY USA.
Journal of acute medicine
|June 10, 2024
概括
在2019年新冠病毒病 (COVID-19) 中受影响的器官系统数量与较差的患者结果相关,包括较高的死亡率和更长的住院时间. 预后工具可以帮助为COVID-19患者量身定制治疗方法.
科学领域:
- 内部医学 内部医学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 众所周知,冠状病毒疾病2019 (COVID-19) 影响多个器官系统.
- 器官系统参与程度与COVID-19预后之间的关系仍未得到充分研究.
研究的目的:
- 调查COVID-19中涉及的器官系统数量与住院死亡率之间的关联.
- 检查COVID-19患者器官系统参与和住院时间 (LOS) 之间的关联.
主要方法:
- 对808名被诊断为COVID-19的连续患者进行了回顾性研究.
- 从2020年3月1日至5月15日期间入住纽约医院的患者收集了数据.
主要成果:
- 受影响的器官系统数量的增加与更高的住院死亡率 (OR: 1.36) 和增加的LOS显著相关.
- 升高的白细胞计数,高的FiO2氧气需求和侵入性机械通风与增加的死亡率有关.
- 增加的肌素和葡萄糖水平与较长的LOS相关.
结论:
- 在COVID-19中,多个器官系统的参与是预后更差的重要指标.
- 反映器官系统参与的临床和实验室参数可以作为指导COVID-19患者治疗策略的宝贵预后工具.
相关概念视频
01:30Pneumonia III: Complications and Assessment
200
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
200
01:20COPD: Pathogenesis and Clinical Features
259
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
259
01:26Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
01:29Pneumonia II: Pathophysiology
255
The pathophysiology of pneumonia involves the following steps:
255
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.7K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.7K
01:18Factors Affecting Illness
4.2K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
4.2K