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在COVID相关的嗅觉障碍的临床研究:机构经验的审查

Theresa Tharakan¹, Dorina Kallogjeri¹, Jay F Piccirillo¹

¹Department of Otolaryngology-Head and Neck Surgery, Clinical Outcomes Research Office, School of Medicine Washington University in St Louis St Louis Missouri USA.

World journal of otorhinolaryngology - head and neck surgery

|June 10, 2024

概括

针对COVID相关的嗅觉功能障碍的临床试验显示,改善气味是有希望的,但目前还没有确定的治疗方法. 为了有效的COVID-19嗅觉丧失疗法,需要进一步的研究.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
传染性疾病传染性疾病
神经学神经学

背景情况:

COVID-19经常导致嗅觉功能障碍 (OD),影响患者的生活质量.
了解和治疗COVID相关的OD是一个重大的临床挑战.

研究的目的:

审查有关COVID相关的嗅觉功能障碍的机构临床研究.
总结COVID-19相关的嗅觉丧失的诊断措施和干预试验的发现.

主要方法:

发表的数据和正在进行的临床试验的叙述性审查 (2020-2023年).
开发和测试新的诊断和患者报告的结果措施.
分析了五项干预试验:视觉嗅觉训练 (VOLT), gabapentin,神灵素灌,星状质阻断和基于正念的减压 (MBSR).

主要成果:

开发了诊断和评估COVID相关OD的三个新措施.
干预试验探讨了各种治疗方法,包括VOLT, gabapentin, theophylline,星状质块和MBSR.
最初的结果表明嗅觉功能可能得到改善,但没有一种治疗方法始终超过安慰剂.

结论:

与COVID相关的OD早期干预试验显示了提高嗅觉结果的潜力.
对于COVID相关的嗅觉功能障碍,还没有确定的,优于安慰剂的治疗方法.
对新型治疗策略的持续研究对于优化COVID-19后嗅觉丧失患者的治疗至关重要.

关键词:

在这里,我们可以看到COVID COVID COVID.化学传感障碍化学传感障碍嗅觉功能障碍嗅觉功能障碍

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