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Updated: Jun 24, 2025

A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy
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从结构设计到交付:用于癌症的mRNA治疗方法 免疫疗法

Feng Zhou1,2, Lujia Huang1,2, Shiqin Li1

  • 1State Key Laboratory of Chemical Biology and Center of Pharmaceutics, Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai China.

Exploration (Beijing, China)
|June 10, 2024
PubMed
概括

使者RNA (mRNA) 疗法通过使细胞产生抗原和免疫调节因子来提供强大的癌症免疫疗法. 输送系统的进步,特别是脂质纳米颗粒,正在克服临床翻译的挑战.

关键词:
癌症免疫疗法免疫疗法以细胞为目标的传递.mRNA 设计的设计在mRNA疗法中使用的mRNA疗法.器官特异性输送器官特异性输送器官

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