数字校准方法使深度分辨率全纤维极化敏感光学连贯性断层扫描能够使用任意输入极化状态
Peijun Tang1, Ruikang K Wang1,2, Qing Chao1
1Department of Bioengineering, University of Washington, 3720 15th Ave NE, Seattle, Washington 98195, USA.
Biomedical optics express
|June 10, 2024
概括
这项研究引入了一种全纤维偏振敏感光学连贯性断层扫描 (PSOCT) 系统. 它可以使用单个任意输入偏振状态进行深度分辨率双折射成像,简化实验程序并提高准确性.
科学领域:
- 生物医学光学 生物医学光学
- 在光学成像系统中,光学成像
- 连贯断层扫描是一致的断层扫描.
背景情况:
- 传统的基于光纤的偏振灵敏光学连贯性断层扫描 (PSOCT) 系统通常需要复杂的设置来生成特定的输入偏振状态.
- 通常需要预调整程序或额外的模块,限制了系统的灵活性和用户友好性.
研究的目的:
- 开发一个完全集成的,全纤维PSOCT系统,能够进行深度分辨率的双折射成像.
- 消除对预定义的输入偏振状态的需求,并简化实验程序.
- 为了弥补光纤引入的偏振状态变化和偏振模式分散 (PMD).
主要方法:
- 使用基于离散微分几何 (DDG) 的极化状态跟踪 (PST) 方法.
- 在斯托克斯空间中使用几何旋转和转换来进行极化分析.
- 实现了一个校准目标,以补偿纤维诱导的偏振变化.
- 对极化模式分散 (PMD) 进行了数字补偿.
主要成果:
- 通过任意的单个输入偏振状态实现了深度分辨率双折射成像.
- 成功地弥补了光纤引入的极化状态变化和PMD.
- 通过塑料幻影和体内皮肤的成像来证明系统的性能.
结论:
- 拟议的全纤维PSOCT系统为双断层成像提供了一种简化,灵活和用户友好的方法.
- 基于DDG的PST方法有效地减轻了PSOCT中光纤相关的挑战.
- 该系统提供准确的深度分辨率PSOCT成像结果,适合各种应用.
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