在进行体外受精刺激后,对子宫腔变化的超声波评估
Irene Peregrin-Alvarez1, Robert Roman2, Leah Schenk1
1Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA.
概括
模拟胚胎移植 (ET) 有助于确定子宫腔长度 (UCL),以获得最佳的体外受精 (IVF) 胚胎放置. 卵巢刺激显著增加UCL,突出显示子宫可塑性,需要在临床ET期间考虑这些变化.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 医疗成像医学成像
- 在体外受精过程中受精.
背景情况:
- 假胚胎移植 (ET) 用于测量子宫腔长度 (UCL),以优化体外受精 (IVF) 期间的临床ET.
- 最佳的怀孕率与从子宫底部15毫米深处的临床ET有关.
- 卵巢刺激和子宫内膜制备对UCL的影响需要进一步调查.
研究的目的:
- 确定卵巢刺激和子宫内膜制备对子宫腔长度 (UCL) 的影响.
- 为了评估UCL的变化,在模拟ET和临床ET期间使用2D腹腔超声波来评估UCL的变化.
主要方法:
- 追溯队列研究,比较UCL的2D横腹腔超声波测量.
- 在91个IVF-ET周期中,在模拟ET和临床ET期间进行了测量.
- 统计分析包括对对的样本t测试 (P < .05).
主要成果:
- 分析了70名患者 (91个IVF-ET周期);中位数年龄为34岁.
- 在IVF刺激后UCL显著增加11.9毫米 (P<.001).
- 平均UCL在模拟ET时为7.66厘米 (±0.98厘米),在临床ET时为8.85厘米 (±0.98厘米).
结论:
- 在卵巢刺激和子宫内膜准备过程中,子宫腔的长度显著变化.
- 激素刺激会在怀孕前引发显著的子宫可塑性.
- 在超声波指导的临床ET期间调整UCL变化对于最佳胚胎放置至关重要.
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