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在分娩期间静脉注射液体与产后主要出血之间的关联:一项回顾性队列研究

Belinda R Bruce^1,2, Heather L Shepherd¹, Saleem Ahmed Khan³

¹Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.

Acta obstetricia et gynecologica Scandinavica

|June 10, 2024

概括

在分娩期间大量静脉注射 (IV) 液体并没有增加产后出血 (PPH) 的风险. 然而,高体积的静脉注射液与有期,单胎妊娠的妇女的剖腹产率更高有关.

科学领域:

产科和妇科产科和妇科
围产儿医学围产儿医学
临床研究临床研究

背景情况:

关于静脉注射 (IV) 流体在分娩期间对母亲和新生儿健康的影响,存在重大知识差距.
一个合理的生物学联系表明,注射IV液体的体积可能会影响初级产后出血 (PPH) 的发生率.

研究的目的:

调查在分娩期间输入大量IV液体 (≥2500毫升) 是否与初级PPH风险增加有关.
评估高容量静脉输液与其他不良孕妇结果之间的关联,包括剖腹产和大围损伤,在有期,单独怀孕的妇女中.

主要方法:

进行了一项回顾性队列研究,涉及1023名妇女,她们在怀孕37至42周之间接受了分娩和分娩.
从电子和纸质记录中收集了IV液体体积,初级PPH (≥500毫升),剖腹产和大围损伤的数据.
使用多变量逻辑回归和多重归算来分析IV液体体积和PPH之间的关系,并根据相关因素进行调整.

主要成果:

在分娩期间输入大量静脉流体和初级PPH发生之间没有发现显著的关联 (调整后OR为1.02;95%CI为0.72,1.44).
在高容量的静脉输液和剖腹产之间观察到一个统计学上显著的积极关联 (调整后OR为1.99;95%CI为1.4,2.8).

结论:

该研究强调,在分娩期间输入大量静脉流体与产后出血风险增加无关.
研究结果强调,需要精确记录分娩期间输入静脉液体的情况,以便更好地了解其对怀孕和围产期结果的全面影响.
需要进一步的研究来阐明IV流体管理在产科护理中的更广泛影响.

关键词:

分娩,产科, 产妇静脉注射液体的使用产后出血产后出血是什么怀孕怀孕怀孕怀孕怀孕怀孕结果怀孕结果水电解质平衡水电解质平衡

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