优化定量化内动脉瘤增强的时间:一个多相对比增强的血管壁MRI研究
Xiao Li1,2, Jianjian Zhang1,2, Jin Zhang1,2
1Department of Radiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
European radiology
|June 10, 2024
概括
在内动脉瘤 (IA) 中量化动脉瘤壁增强 (AWE) 的最佳时间因类型而异. 聚合型IA在对比后立即显示最强的AWE,而状IA在36分钟内保持稳定.
科学领域:
- 神经成像是一种神经成像.
- 血管医学 血管医学
- 放射学 放射学是一门学科.
背景情况:
- 动脉瘤壁增强 (AWE) 在高分辨率对比增强的血管壁MRI (VWMRI) 上是对内动脉瘤 (IA) 稳定性的新兴生物标志物.
- 目前用于AWE的量化方法是可变的,需要标准化.
研究的目的:
- 为了确定最佳的后对比时间来量化AWE在状和状IA中.
- 为了比较囊状和状IA亚型之间AWE的动态变化.
主要方法:
- 预期招募患有未破裂IA的患者.
- 获取VWMRI,具有1个前对比和4个连续的后对比阶段.
- 测量脑脊液和动脉瘤壁的信号强度,以计算动脉瘤壁增强指数 (WEI) 和定性AWE分级.
主要成果:
- 融合型IA的WEI随着时间的推移下降了22.0% (p=0.009).
- 囊性IA的WEI在对比后阶段保持不变 (p>0.05).
- 在30%的状和40%的状IA中观察到AWE等级的动态变化.
结论:
- 对于定量AWE分析,立即对比后的VWMRI是状IA的最佳选择.
- 在囊性IA中,AWE在对比剂注射后至少36分钟保持稳定.
- 对AWE的成像协议和分析方法的标准化对于IA管理中的监测和治疗决策至关重要.
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