大肢截肢后的神经病痛:一个横截面研究
Mirte Langeveld1, Floris V Raasveld1,2, Caroline A Hundepool1
1From the Department of Plastic, Reconstructive Surgery, and Hand Surgery.
Plastic and reconstructive surgery
|June 10, 2024
概括
截肢后的神经病残留肢体疼痛 (RLP) 是常见的,影响超过20%的患者,并降低了生活质量. 由于有限的可管理的预后因素,截肢时的预防性干预可能至关重要.
科学领域:
- 截肢和疼痛管理
- 神经学 神经学
- 康复医学 康复医学 康复医学
背景情况:
- 剩余四肢疼痛 (RLP) 和幻肢疼痛是截肢后常见的并发症.
- 这些情况可能需要进一步的医疗干预或外科手术.
- 识别神经病性RLP的患病率和预后因素对于有效管理至关重要.
研究的目的:
- 为了确定肢体截肢后的神经病性RLP的患病率.
- 确定与神经病性RLP发展相关的预后因素.
- 评估神经病性RLP对截肢者的生活质量的影响.
主要方法:
- 一项横截面研究包括121名上肢或下肢截肢患者 (1990-2021年).
- 神经病性RLP是由疼痛得分 (≥4/10) 和神经病性疼痛4问卷得分 (≥4) 定义的.
- 多变量线性回归分析了神经性RLP的预后因素.
主要成果:
- 神经病性RLP的患病率为21.5%,非神经病性RLP为10.7%.
- 吸烟和复杂区域疼痛综合征 (CRPS) 作为截肢指示与更严重的神经病痛相关.
- 患有神经性RLP的患者报告生活质量明显降低.
结论:
- 神经病性RLP是截肢后的一个普遍且具有影响力的疾病.
- 可管理的预后因素的稀缺性强调了早期考虑预防措施的必要性.
- 截肢期间的干预措施可以减轻神经病性RLP的发展和影响.
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