神经肌肉疾病中呼吸道肌肉训练的未来方向:一个范围审查
Esmee S B van Kleef1, Diego Poddighe2,3, Mayra Caleffi Pereira2,3,4
1Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands, esmee.vankleef@radboudumc.nl.
Respiration; international review of thoracic diseases
|June 10, 2024
概括
呼吸道肌肉训练 (RMT) 在神经肌肉疾病 (NMDs) 中显示出对呼吸强度的可变影响. 观察到高坚持性和没有严重的不良事件,但研究设计的多样性限制了结论.
科学领域:
- 神经学 神经学
- 肺部病理学 肺部病理学
- 康复医学 康复医学 康复医学
背景情况:
- 神经肌肉疾病 (NMDs) 通常会损害呼吸道肌肉功能.
- 呼吸肌肉训练 (RMT) 是一种潜在的干预措施,可以改善NMD患者的呼吸功能.
- 需要对NMD中的RMT进行全面审查.
研究的目的:
- 在NMD中进行RMT研究的范围审查.
- 探索RMT干预的方法特征,效果和坚持.
- 确定研究缺口,并建议未来的研究方向.
主要方法:
- 搜索了主要的数据库 (MEDLINE,Embase,Cochrane) 的相关研究.
- 包括RMT设备在NMD患者肺功能结果的原始研究文章.
- 排除了重症患者,机械通风和联合干预.
主要成果:
- 分析了45项不同设计和培训方案的研究.
- 观察到RMT对呼吸肌肉强度和耐力的影响.
- 报告了高的患者坚持和没有严重的不良事件.
结论:
- 在RMT研究中的多样性阻止了关于NMDs有效性的最终结论.
- 需要进一步进行有力的,精心设计的研究.
- 未来的研究应该专注于临床相关的结果,以评估RMT对NMDs呼吸系统衰弱的影响.
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