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Updated: Jun 24, 2025

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
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在肝内胆管癌中,PARP-1 选择性地损害KRAS驱动的表型和分子特征

Friederike L Keggenhoff1, Darko Castven2, Diana Becker1

  • 1First Department of Internal Medicine, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

Gut
|June 10, 2024
PubMed
概括

聚 ((ADP-ribose) 聚合酶1 (PARP-1) 抑制会影响KRAS突变性肝脏内胆固醇癌 (iCCA) 的生长. 在KRAS突变iCCA中PARP-1耗尽提供了一个新的治疗策略和预后标记.

关键词:
致癌的发生是致癌性.查兰吉奥卡尔奇诺马马 查兰吉奥卡尔奇诺马基因突变是一种基因突变.分子瘤学分子瘤学

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