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Updated: Jun 24, 2025

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一个青少年的单克隆IgG沉积的增殖性淋巴结膜炎成功地用daratumumab治疗

Eva Svabova1, Jakub Zieg2, Martina Sukova3

  • 1Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic. eva.svabova@fnmotol.cz.

Pediatric nephrology (Berlin, Germany)
|June 10, 2024
PubMed
概括

在儿童中,具有单克隆IgG沉积 (PGNMID) 的增殖性淋巴结膜炎缺乏特定的治疗方法. 一名患有PGNMID的15岁男孩在针对CD38血细胞的达拉图穆马布治疗后显示出显著的脏改善.

关键词:
青少年是一个青少年.达拉图姆巴姆巴姆增殖性淋巴细胞突炎与单克隆IgG沉积物蛋白质尿症是一种蛋白质尿症.

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Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
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Commonly used fusion techniques — electroporation,...
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