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Updated: Jun 24, 2025

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
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异常的ER-线粒体通信是线粒体疾病中常见的病理机制

Patricia Morcillo1, Khushbu Kabra2, Kevin Velasco2

  • 1Department of Neurology, Columbia University Medical Center, New York, NY, 10032, USA. phd.morcillo@gmail.com.

Cell death & disease
|June 10, 2024
PubMed
概括

主要线粒体疾病涉及影响氧化酸化 (OxPhos) 的遗传突变. 在MAMs中,细胞内网膜 (ER) 和线粒体之间的通信中断导致疾病变异性和细胞死亡,超出了减少的能量输出.

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