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Updated: Jun 24, 2025

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通过使用药理动力学建模方法研究布里瓦拉的临床药理动力学

Attia Qayyum1, Ammara Zamir2, Muhammad Fawad Rasool3

  • 1Department of Pharmacology, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 60800, Pakistan.

Scientific reports
|June 10, 2024
PubMed
概括

这项研究开发了一种基于生理学的药理动力学 (PBPK) 模型,用于布里瓦拉 (BRV) 预测健康和患病人群的药物行为. 该模型精确模拟了BRV的药理动力学,有助于对肝脏和脏功能障碍进行剂量调整.

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