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Updated: Jun 24, 2025

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在肝细胞癌中,MLK3通过TGFβ通路促进了亲瘤信号传递

Rong Ke1,2, Navin Viswakarma1,3, Mary Menhart4

  • 1Department of Surgery, Division of Surgical Oncology, University of Illinois at Chicago, Chicago, IL, 60612, USA.

Oncogene
|June 10, 2024
PubMed
概括

混合血统激酶3 (MLK3) 通过促进细胞增殖和上皮-介质细胞转换 (EMT) 来驱动肝细胞癌 (HCC) 的进展. 针对MLK3-TGFβ轴为高级HCC提供了一个有希望的治疗策略.

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