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Updated: Jun 24, 2025

Generation of Orthotopic Pancreatic Tumors and Ex vivo Characterization of Tumor-Infiltrating T Cell Cytotoxicity
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γδ T 细胞和PD-1/PD-L1轴:瘤微环境中的爱恨关系

Jian Liu1, Min Wu2, Yifan Yang1

  • 1Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Journal of translational medicine
|June 10, 2024
PubMed
概括

马三角形 (γδ) T 细胞在癌症治疗中表现有前途,但受到瘤微环境的阻碍. 了解PD-1/PD-L1轴对γδT细胞的影响对于改善免疫治疗至关重要.

关键词:
抗瘤免疫疗法免疫疗法免疫检查点抑制剂 (ICI)免疫检查站 (ICP) 是一个检查站.免疫抑制分子 免疫抑制分子在PD-1/PD-L1中.瘤微环境 (TME) 是指瘤的微环境.γδ T 细胞的 T 细胞

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