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Updated: May 12, 2026

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
10:01

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Published on: November 28, 2017

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同时对单个和双重突变的原生质谱分析,以检测脂质与膜蛋白的结合

Hiruni S Jayasekera1, Farhana Afrin Mohona1, Megan Ewbank1

  • 1Department of Chemistry and Biochemistry and Bio5 Institute, University of Arizona, Tucson, Arizona 85721, United States.

Analytical chemistry
|June 11, 2024
PubMed
概括

这项研究引入了一种新的原生质谱法 (MS) 方法来量化脂蛋白相互作用. 该方法精确地测量了像W14和R224这样的特定残留物的能量贡献,以与Aquaporin Z (AqpZ) 结合心血管蛋白.

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Peptide Identification Using Tandem Mass Spectrometry

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Tandem Mass Spectrometry

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