在怀孕和产后期间,宫阴道液中埃法维伦兹暴露的药物遗传学

Oluwasegun Eniayewu1, Uche Azuka2, Jonah Ogah2

  • 1Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, Nigeria.

概括

怀孕和CYP2B6遗传变异显著影响子宫流体 (CVF) 中的埃法维伦兹水平. 怀孕期间,CVF中的efavirenz度较低,特别是在具有特定CYP2B6基因型的女性中.

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