青春期的口吃和早期成年期失糖症的风险
Alexandra Rabotin1,2, Yair Schwarz2,3, Orit Pinhas-Hamiel2,4
1The Israel Defense Forces Medical Corps, Ramat Gan, Israel.
Diabetes/metabolism research and reviews
|June 11, 2024
概括
青少年口吃与男性和女性在成年早期患上失糖症风险增加有关. 建议采取有针对性的查和预防策略,特别是针对女性.
科学领域:
- 内分泌学和代谢障碍 代谢障碍
- 神经发育障碍 神经发育障碍
- 公共卫生 公共卫生
背景情况:
- 低血糖症包括糖尿病前期和2型糖尿病,是全球严重的健康问题.
- 青少年口吃是一种影响言语流性的神经发育状况.
- 吃对健康的长期影响,特别是对代谢健康的影响,需要进一步研究.
研究的目的:
- 检查青春期口吃与早期成年期随后发展的失糖症之间的关联.
- 为了区分口吃的男性和女性之间的风险.
- 为风险人群提供潜在的公共卫生干预信息.
主要方法:
- 这是一项大型的队列研究,对866304名在1990-2019年期间被评估为服兵役的人进行了评估.
- 在基线时记录了口吃状态;在2020年12月之前,通过注册表追踪了失糖症 (糖尿病前期/2型糖尿病).
- 使用考克斯的比例危险模型,对男性和女性进行单独分析,并对共变量进行调整.
主要成果:
- 与没有口吃的人相比,口吃的个体患糖尿病的风险明显增加 (男性的aHR为1.18;女性为1.61).
- 吃的女性患有失糖症的发病率最高 (102.3每10,000人年).
- 这些关联在广泛的子分析中保持一致.
结论:
- 青少年的口吃是早期成年期患上失糖症的重要危险因素.
- 在口吃的女性中观察到的风险增加需要特别注意.
- 对于口吃的青少年,应考虑早期查和糖尿病预防措施.
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