采用CRISPR-Cas用于作物生产:现状和未来前景
Akinlolu Olalekan Akanmu1, Michael Dare Asemoloye1, Mario Andrea Marchisio2
1Food Security and Safety Focus Area, Faculty of Natural and Agricultural Sciences, University of North-West, Mmabatho, South Africa.
PeerJ
|June 11, 2024
概括
全球粮食系统面临环境压力因素和病原体带来的挑战. 集群定期间隔的短时间Palindromic重复 (CRISPR) -Cas技术为增强作物耐药性,改善粮食安全和确保可持续农业提供了一个有希望的遗传解决方案.
科学领域:
- 农业科学 农业科学
- 生物技术是生物技术.
- 粮食安全 粮食安全
背景情况:
- 全球粮食系统越来越受到环境挑战和人为活动的威胁,导致粮食生产,安全和质量下降.
- 包括抗生素耐药性病原体在内的生物和非生物压力因素对农场到叉子连续的作物产量和食品污染构成重大风险.
- 全球人口不断增长需要强大的食品系统,优先考虑安全,质量和一致的可用性.
研究的目的:
- 审查有关食品系统和植物疾病管理策略的当前知识.
- 探索遗传学方法的潜力,特别是集群定期间隔的短Palindromic重复 (CRISPR) 和Cas (CRISPR相关) 蛋白质技术,以提高粮食安全.
- 突出先进基因组编辑在实现可持续农业中的作用.
主要方法:
- 在多个数据库中进行了全面的文献搜索,重点关注食品系统和植物疾病管理.
- 特别注意的是基因工程方法,特别强调CRISPR-Cas技术.
- 对改善作物的基因组编辑技术现有研究的分析.
主要成果:
- 目前正在开发各种方法来增强作物耐药性,包括增强系统性耐药性和设计抗病原体的品种.
- 克里斯普尔-卡斯技术已经成为精确基因编辑作物的强大工具,可以同时修改多个农学特征.
- 该技术显示了提高作物弹性,产量和质量的巨大潜力.
结论:
- 克里斯普尔-卡斯技术对于开发抗病和抗干旱作物至关重要,从而提高食品质量和产量.
- 尽管正在进行安全讨论,但CRISPR-Cas为可持续的食品管理和安全提供了巨大的好处.
- 这项技术是农业应用中传统基因组编辑方法的关键进步.
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