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随机对照试验RELAX:夜间肌肉的伸展与冥想
Elliot B Tapper1, Hirsh Trivedi2, Douglas A Simonetto3
1Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA.
概括
拉伸和冥想都有效地减少了肌肉的严重程度,并改善了肝硬化患者的睡眠质量. 虽然患者更喜欢伸展,但这两种干预措施在这种随机试验中表现出可比的疗效.
科学领域:
- 肝病学和胃肠道学
- 神经学 神经学
- 补充和替代医学 补充和替代医学
背景情况:
- 肌肉抽筋是肝硬化患者普遍存在的问题,严重损害了他们的生活质量.
- 目前这种人群肌肉的治疗选择有限,需要进一步研究有效的干预措施.
研究的目的:
- 为了比较拉伸与冥想在减少肌肉的严重程度的疗效,在肝硬化患者中.
- 评估这些干预措施对睡眠质量,患者对变化的总体印象和与健康有关的生活质量 (HRQOL) 的影响.
主要方法:
- 一项随机对照试验 (RCT) 涉及98名患有频繁肌肉的患者.
- 参与者被随机分配到35天的拉伸或冥想组.
- 主要结局:的严重程度的变化 (的视觉模拟尺度 - VAS-cramps). 二级结局:患者的全球变化印象 (PGIC),睡眠质量和HRQOL (EQ-5D和VAS-全球HRQOL).
主要成果:
- 伸展和冥想都显著降低了的严重程度 (分别p < .001和p < .0001),两组之间没有显著差异 (p = .4).
- 在这两种干预措施中,睡眠质量和PGIC均有所改善.
- 虽然HRQOL在冥想 (VAS) 中得到改善,但在拉伸 (EQ-5D) 中没有显著变化. 患者偏好倾向于伸展 (79.2%对55.3%).
结论:
- 伸展和冥想都有效地减少肌肉的严重程度,并改善肝硬化患者的睡眠质量.
- 尽管患者倾向于伸展,但在伸展和冥想之间没有发现治疗效果的显著差异.
- 进一步的研究可能会探索每个干预措施的具体机制和长期益处.
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