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相关概念视频

Electrophilic Aromatic Substitution: Sulfonation of Benzene01:22

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Sulfonation of benzene is a reaction wherein benzene is treated with fuming sulfuric acid at room temperature to produce benzenesulfonic acid. Fuming sulfuric acid is a mixture of sulfur trioxide and concentrated sulfuric acid.
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Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.
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A Web Tool for Generating High Quality Machine-readable Biological Pathways
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MakeSBML:一个用于在Antimony和SBML之间进行转换的工具.

Bartholomew E Jardine1, Lucian P Smith1, Herbert M Sauro1

  • 1Department of Bioengineering, University of Washington, Box 355061, Seattle, 98195, WA, USA.

Journal of integrative bioinformatics
|June 11, 2024
PubMed
概括
此摘要是机器生成的。

MakeSBML是一个免费的,基于Web的工具,用于在系统生物学标记语言 (SBML) 中创建和编辑系统生物学模型. 它简化了使用人类可读的Antimony语言创建模型,提高了研究人员的可访问性.

关键词:
它们是反的.这是SBML的SBML.建模建模是什么意思反应网络的反应网络.软件软件 软件 软件 软件 软件系统生物学 系统生物学

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科学领域:

  • 系统生物学 系统生物学
  • 计算生物学 计算生物学
  • 生物信息学是一种生物信息学.

背景情况:

  • 系统生物学标记语言 (SBML) 对于描述生化网络至关重要,但它是计算机可读的,而不是人类可读的.
  • 创建和编辑SBML模型可能是复杂的,阻碍了系统生物学研究中的可复制性和可访问性.

研究的目的:

  • 介绍MakeSBML,一个免安装的,基于Web的应用程序,用于创建,编辑和搜索SBML模型.
  • 通过使人类可读的Antimony和SBML之间的翻译,促进SBML在系统生物学中的使用.

主要方法:

  • 开发了一个基于客户端的Web应用程序,MakeSBML,可以通过GitHub页面访问.
  • 在Antimony语言和SBML之间实现了翻译功能.
  • 设计用于无需安装的使用,不需要主动服务器维护.

主要成果:

  • MakeSBML提供了一个用户友好的界面,用于生成和修改符合SBML的模型.
  • 该工具支持Antimony和SBML格式之间的双向转换.
  • 基于Web的客户端架构简化了部署,并减少了维护开销.

结论:

  • 在系统生物学中,MakeSBML提高了SBML建模的可访问性和可用性.
  • 该工具通过简化复杂生物模型的创建和编辑来促进模型的可重现性和协作.
  • 它的免安装,基于网络的性质使得它成为系统生物学社区容易获得的资源.