解读妊娠晚期萨希瓦尔奶牛在不同微气候下的免疫反应及其对后代的传递效应
Vishwa Ranjan Upadhyay1,2, Ashutosh3, C G Shashank3
1ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India. vishwaranjanhzb@gmail.com.
International journal of biometeorology
|June 11, 2024
概括
在孕期晚期的热应激会对小牛的免疫力和生长产生负面影响. 缓解热应激对于母亲的健康和后代的发展至关重要.
科学领域:
- 动物科学动物科学
- 生殖生物学 生殖生物学
- 环境生理学环境生理学
背景情况:
- 孕期晚期的热应激 (HS) 对母亲和胎儿的健康构成风险.
- 了解暴露于子宫内热应激的小牛的炎症和免疫反应至关重要.
研究的目的:
- 为了研究在妊娠晚期遭受热应激的子宫内小牛的炎症和免疫反应.
- 评估热应激对萨希瓦尔牛及其小牛生理参数和生物标志物的影响.
主要方法:
- 在怀孕晚期的48头Sahiwal奶牛被分为自然热应激 (NHS),冷却处理 (CLT),春季和冬季组.
- 记录了环境参数 (THI) 和生理数据 (RT,RR,PR,ST).
- 分析了血生物标志物 (皮质醇,IL-6,TNF-α,TBARS,TAC,IgG) 和小牛的体重.
主要成果:
- 在NHS和春季组体验了热应激 (THI>76.00).
- 在NHS的奶牛和子宫内热应激 (IUHS) 的小牛中,炎症标志物 (IL-6,TNF-α,TBARS) 较高,抗氧化能力 (TAC) 和IgG较低.
- 在整个研究过程中,IUHS小牛的体重显著降低.
结论:
- 孕期晚期的热应激会在发育中的小牛中引起有害的生理变化.
- 减轻热应激的缓解策略对于水的生产力和小牛的发育至关重要.
- 热应激会影响小牛的免疫状态,氧化平衡和生长轨迹.
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