儿科呼吸道同胞性病毒住院情况,2017-2023年
Tiffany Fitzpatrick1,2,3,4, Sarah A Buchan1,2,3,4,5, Sanjay Mahant6
1Public Health Ontario, Toronto, Ontario, Canada.
JAMA network open
|June 11, 2024
概括
在COVID-19后,2022-2023赛季,儿童的呼吸系统综合体病毒 (RSV) 住院病例显著增加,并观察到更高的重症监护室 (ICU) 住院率. 年龄较大的儿童在季后出现更高的住院率.
科学领域:
- 儿童传染病 儿童传染病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 呼吸道同胞病毒 (RSV) 传播模式在全球范围内因COVID-19大流行而发生变化.
- 了解这些变化对于管理儿科呼吸道疾病至关重要.
研究的目的:
- 为了比较观察到的与预期的RSV相关住院和重症监护室 (ICU) 在5岁以下儿童的入院率.
- 与大流行前时期相比,分析2021-2022年和2022-2023年RSV季节入院儿童特征的变化.
主要方法:
- 加拿大安大略省的一项基于人口的队列研究分析了2017年7月1日至2023年3月31日的数据.
- 每年包括大约70万名儿童,检查社会人口统计学和临床因素.
- 使用Poisson概括估计方程来建模住院率和估计预期率.
主要成果:
- 在2022-2023年RSV季节,与大流行前年相比,住院病例的数量翻了一番 (770.0 vs 281.4-334.6 / 100,000).
- 在2022-2023年,重症监护室的入院率是大流行前的三倍 (106.9对每10万人的27.6-36.6).
- 在2022-2023年,年龄较大的儿童 (24-59个月) 的住院率明显更高 (RR,1.90).
结论:
- 在COVID-19后的安大略省发生了RSV流行病学的显著偏差.
- 这些非典型RSV流行病的持续时间仍然不确定.
- 医疗保健能力和免疫计划规划必须考虑到潜在的持续RSV影响.
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