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Updated: Jun 24, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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内源性p53抑制剂TIRR将全身代谢健康与瘤性活性分离

Eva Tsaousidou1, Jędrzej Chrzanowski2, Pascal Drané3

  • 1Sabri Ülker Center for Metabolic Research, Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

Cell reports
|June 11, 2024
PubMed
概括

删除Tudor相互作用修复调节器 (TIRR) 激活瘤抑制器p53,减少癌症,但导致肥胖和胰岛素抵抗等代谢问题. 这突显了癌症保护和代谢健康之间的权衡.

关键词:
CP: 癌症 癌症 癌症CP:新陈代谢过程中的新陈代谢.癌症的代谢 癌症的代谢癌症小鼠模型的p53激活的模型.癌症保护 保护 癌症在癌症的体内生理学.梅瓦诺酸路径抑制抑制肥胖和癌症的关系超重和癌症的关系在 p53 激活过程中,p53 激活会发生.p53 减压的方法这是一种p53抑制剂.2型糖尿病和癌症的第二种类型.

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