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在急性肺栓塞中,碎片化QRS复合体的动态变化的重要性
1Department of Cardiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, PR China.
Heart & lung : the journal of critical care
|June 11, 2024
概括
碎片化QRS (fQRS) 复合体的动态变化预测急性肺栓塞 (APE) 患者的结果. 较浅的fQRS表明预后良好,而更深的fQRS表明预后不佳,有助于风险分层.
科学领域:
- 心脏病学 心脏病学
- 肺部医学 肺部医学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 在急性肺栓塞 (APE) 系列心电图上,碎片化QRS (fQRS) 综合体的动态变化未得到研究.
- 了解这些心电图变化可以为APE患者的预后提供见解.
研究的目的:
- 在被诊断为APE的患者中调查fQRS复合体动态变化的预后意义.
- 为了将fQRS复杂的变化与APE的长期结果相关联.
主要方法:
- 222名APE患者根据入院至1个月随访期间的fQRS变化被分为三个组:浅,深或不变.
- 对患者进行了12个月的监测,以评估长期死亡率和无事件生存率.
主要成果:
- 一个动态更深的fQRS复合体独立预测了APE患者的长期死亡率 (HR:5.563,P = 0.040).
- 卡普兰-梅尔分析显示,较浅的fQRS组与较深的fQRS组相比,无事件生存率显著增加 (P = 0.022).
- 较深的fQRS组与较浅和不变的组相比,无事件生存率显著下降 (P = 0.041).
结论:
- 动态较浅的fQRS复合体意味着APE的良好预后,而动态较深的fQRS复合体则表明预后不佳.
- 连续fQRS复杂变化可以帮助临床医生进行APE风险分层和个性化治疗策略.
- 监测fQRS动态可能有助于预测APE患者的疾病回归或进展.
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