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相关概念视频

The Thyroid Gland01:23

The Thyroid Gland

3.8K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
3.8K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

2.7K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.5K
Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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相关实验视频

Updated: Jun 24, 2025

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

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甲状腺内胸腺癌 甲状腺内胸腺癌

Caroline Lee Chun Yun1, Ming Yann Lim2, Manish M Bundele3

  • 1Department of Otorhinolaryngology, Khoo Teck Puat Hospital, Singapore carolineleechunyun@gmail.com.

BMJ case reports
|June 11, 2024
PubMed
概括

诊断罕见的甲状腺内胸腺癌 (ITC) 是具有挑战性的,通常需要免疫组织化学. 这一案例凸显了手术上的困难以及对这种罕见的甲状腺癌最佳治疗策略的进一步研究的需要.

关键词:
耳鼻喉科/耳鼻喉科 耳鼻喉科在瘤学瘤学.甲状腺腺是什么?甲状腺是什么?

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相关实验视频

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科学领域:

  • 内分泌学 在内分泌学.
  • 在瘤学瘤学.
  • 病理学 病理学 病理学

背景情况:

  • 甲状腺内胸腺癌 (ITC) 是一种非常罕见的甲状腺恶性瘤.
  • 对罕见的甲状腺癌进行准确的术前诊断仍然是一个重大的临床挑战.
  • 声带可以表明晚期甲状腺病理,涉及复发性喉神经.

研究的目的:

  • 报告一种甲状腺内胸腺癌病例.
  • 突出诊断挑战,并强调免疫组织化学的作用.
  • 审查文献并讨论这种罕见癌症的治疗影响.

主要方法:

  • 一个年轻女子患有甲状腺质量的案例介绍.
  • 手术干预:全甲状腺切除和部剖析.
  • 组织病理学检查和免疫组织化学染色以确定诊断.

主要成果:

  • 最终的组织病理学证实了甲状腺内胸腺癌.
  • 瘤是侵入性的,涉及邻近的结构,需要牺牲复发性喉神经.
  • 建议在多学科瘤委员会审查后进行辅助放射治疗.

结论:

  • 甲状腺内胸腺癌的术前诊断是困难的.
  • 免疫组织化学染色对于准确诊断ITC至关重要.
  • 由于ITC的罕见性,需要进一步的研究和共识,以确定ITC的最佳治疗策略.