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Updated: Jun 24, 2025

Analysis of Transforming Growth Factor ß Family Cleavage Products Secreted Into the Blastocoele of Xenopus laevis Embryos
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BMP信号控制的分子机制通过扭曲的胃流动来控制

Tomas Malinauskas1, Gareth Moore2, Amalie F Rudolf3

  • 1Division of Structural Biology, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK. tomas@strubi.ox.ac.uk.

Nature communications
|June 11, 2024
PubMed
概括

扭曲胃流动 (TWSG1) 是一种分泌的葡萄糖蛋白,它调节骨形态遗传蛋白 (BMP) 信号传递. 晶体结构显示,TWSG1通过阻断受体结合,一种跨物种保存的机制来抑制BMPs.

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