在后COVID综合征,COVID-19康复者和COVID-19原始个体中客观和主观认知功能的概况
A R Bland1, M Barraclough2,3, W R Trender4
1Department of Psychology, Manchester Metropolitan University, Manchester, UK. a.bland@mmu.ac.uk.
Scientific reports
|June 11, 2024
概括
在COVID-19之后,像记忆和注意力问题这样的持续性认知问题很常见. 在暴露于急性COVID-19的个体中观察到客观认知缺陷,在康复的患者中随着时间的推移得到改善,但在后COVID综合征中持续存在.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 后COVID综合征 (PCS) 呈现出持续的认知困难,影响记忆和注意力.
- 据报道,即使在从急性COVID-19中完全康复的个体中,也会出现认知障碍.
- 主观"脑雾"与客观认知功能障碍之间的关系需要进一步研究.
研究的目的:
- 调查PCS患者,康复的COVID-19患者和对照者的客观和主观认知困难.
- 探索自我报告的疲劳和压力与认知缺陷的关联.
- 为了确定急性COVID-19感染的长期认知影响.
主要方法:
- 162名参与者 (50名PCS,59名康复者,53名对照人) 完成了在线问卷和神经认知任务.
- 通过认知失败问卷评估主观认知功能.
- 使用Cognitron认知测试电池测量目标认知功能.
主要成果:
- 主观认知缺陷与感知到的压力和疲劳相关,而不是COVID-19状态.
- 在有COVID-19感染史的个人中发现了客观认知缺陷,不论PCS.
- 在康复的个体中,客观认知功能随着时间的推移而改善,但在PCS患者中仍然存在.
结论:
- 自我报告的"脑雾"并不一定反映了客观测量的认知功能障碍.
- 急性COVID-19感染可以导致持久的客观认知缺陷,即使没有持续的症状.
- 在完全康复的个体中观察到认知恢复,而持续的缺陷则是后COVID综合征的特征.
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