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实验性结肠炎的循环时间依赖性影响对神素的处置和毒性

Yi Yang1, Pengcheng Wu2, Juntao Guo3

  • 1Department of Metabolic and Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.

British journal of pharmacology
|June 11, 2024
PubMed
概括

炎症性肠病 (IBD) 以时间依赖的方式改变药物代谢和毒性,与中断的昼夜节律和BMAL1功能有关. 这影响了IBD患者的药物疗效和安全性.

关键词:
在 BMAL1 中,在CYP1A2中.在CYP2E1中.昼夜时钟是生物周期的时间表.大肠炎是一种大肠炎.药物处置 药物处置 药物处置

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